Ngokwembono yembali yophuhliso loshishino lwamayeza aseTshayina, emva kweminyaka ephantse ibe yi-30 yophuhliso, abangeneleli bamayeza baye baphuhla ukusuka kwisebe elincinane leshishini lemichiza ukuya kwishishini elikhulayo elinexabiso lemveliso yeebhiliyoni zeeyuan, kwaye ukhuphiswano lwayo lwentengiso luye lwaphuhlisa. ziba neengcwangu.

Kuyaqondwa ukuba kwinqanaba lokuqala lophuhliso loshishino lwamayeza aphakathi, ngenxa yotyalo-mali oluncinci kunye nezinga eliphezulu lokubuya, amashishini aphakathi amayeza axubile njengekhowa, ngakumbi eZhejiang, eTaizhou, eNanjing nakweminye imimandla eneemeko ezifanelekileyo zophuhliso lwe. uphuhliso lwamaziko amayeza lukhawuleza kakhulu.

Okwangoku, njengoko utshintsho lwepateni yemarike yonyango, kunye nokuveliswa kwamachiza amatsha emarikeni kulinganiselwe, ubunzima be-pharmaceutical intermediates kushishino lophuhliso lwemveliso entsha luba lukhulu ngakumbi, imveliso yemveli iya isiba ukhuphiswano oluqatha. , i-mediated media media profits yawa ngokukhawuleza, kwaye abaphakathi bamayeza baba yinto yokucinga malunga nengxaki yendlela yokuphuhliswa kweshishini.

Ishishini likholelwa ukuba kunokwenzeka ukwenza inzuzo yalo yokhuphiswano ukusuka kwimiba yetekhnoloji, impembelelo kunye notshintsho, ukuze ugqame kwimarike.

Ngokwethekhinoloji, ikakhulu ibhekisa ekuphuculeni itekhnoloji kunye nokonga iindleko.Kuxelwa ukuba indlela yenkqubo yoxubo-mayeza inde, inyathelo lokusabela likhulu, ukusetyenziswa kwe-solvent inkulu, amandla okuphucula ubugcisa mkhulu.

Ngokomzekelo, kunokusetyenziswa izixhobo ezingaphantsi kwexabiso eliphantsi endaweni yezixhobo ezixabisekileyo, ezifana ne-bromide engamanzi ekuveliseni i-aminothioamidic acid kunye ne-ammonium thiocyanate kwimveliso endaweni ye-potassium thiocyanate (sodium).

Ukongezelela, i-solvent enye ingasetyenziselwa ukutshintsha i-solvents ezahlukeneyo kwinkqubo yokuphendula, kunye ne-alcohol eveliswa kwi-hydrolysis yeemveliso ze-ester zingabuyiswa.

Ngokubhekiselele kwimpembelelo, ubukhulu becala yenze imveliso yayo kwaye iphucule impembelelo yayo kwishishini.Kuyaqondwa ukuba ngenxa yokhuphiswano olunzima lwe-homogenization yemveliso kwishishini lamayeza aseTshayina, ukuba amashishini anokwenza iimveliso zawo eziluncedo, ngokuqinisekileyo baya kuba nakho. iinzuzo ezininzi kwimarike.

Ngokubhekiselele kwinguqu, ngoku, kunye neemfuno ezingqongqo zokukhuselwa kwendalo e-China, izibonelelo zithambekele kumashishini anexabiso eliphezulu, kunye nokunyuka kweendleko zokusingqongileyo, ukuguqulwa kuye kwaba yingxaki ekufuneka iqwalaselwe uphuhliso oluzinzileyo. yamashishini aphakathi amayeza.

Kucetyiswa ukuba amashishini aphakathi axuba amayeza kufuneka andise ikhonkco lemizi-mveliso phezulu nasezantsi, kwaye ajike ezona mathiriyeli ikrwada azisebenzisayo zibe yimveliso yazo. Ngale ndlela, iindleko zinokuncitshiswa ngakumbi, kwaye kwezinye izinto ezikhethekileyo, ukulawulwa kwezixhobo eziphambili kunokuphetshwa.

Ishishini lithi i-spiral ezantsi, apho i-pharmaceutical intermediate idityaniswa ngokuthe ngqo kwi-apis, inokunyusa ngakumbi ixabiso elongezelelweyo leemveliso ngelixa lithengisa ngokuthe ngqo kwiinkampani zamachiza.Kufanelekile ukuba kuqatshelwe ukuba kukho utyalo-mali olukhulu kulwandiso olusezantsi, ngokunjalo. njengemfuno ephezulu yeteknoloji yokuvelisa kunye nobudlelwane obuhle kunye nabasebenzisi be-API. Ngokubanzi, amashishini ahamba phambili aya kufumana inzuzo eninzi yokukhuphisana.

Ukongeza, UPHANDO nophuhliso lubaluleke kakhulu kushishino oluphakathi. Okwangoku, ishishini eliphakathi lamayeza laseTshayina linika ingqwalasela encinci kuphando kunye nophuhliso.Ngoko ke, kwimeko yokuphucula rhoqo iimfuno zobugcisa, amashishini asebenzayo eR&D anamandla aqinileyo eR&D aya kuza ngaphambili, ngelixa amashishini amancinci naphakathi angenawo amandla e-r&d. kupheliswa yimarike. Kwixesha elizayo, ugxininiso loshishino luya kuphuculwa ngakumbi kwaye inqanaba lophuhliso eliphakathi kunye nelokugqibela liya kuphuhliswa ukuya kwinqanaba eliphezulu.