Inqanaba eliphezulu lokucoceka kwe-1,1,3-trichloroacetone yokulungiselela

Abstract:i-acetone catalyzed chloride kwaye iveliswe yi-solvent crystallization kwi-1,1,3-trichloroacetone enobunyulu obuphezulu obungekho ngaphantsi kwe-99.0%, kunye nesivuno se-45% o Amagama angundoqo:1,1,3-trichloroacetone;synthesis;ucoceko oluphezulu

-----------.Intshayelelo

I-1,1,3■i-trichloroacetone siphakathi esibalulekileyo ekuvelisweni kwe-folic acid.Okwangoku,1,1,3.i-acetone trichlorropacetone,umjikelo omde wemveliso(iiyure ezingama-48),ukhetho olulambathayo,isivuno esiphantsi,1,1,3- Umxholo we-trichloropacetone umalunga ne-17% kuphela, emva kokutsalwa kwamanzi, umxholo wayo ngu-51.9% kuphela. Kwaye iindleko zokuvelisa ziphezulu, ukulungiswa kwemveliso kuphantsi.Onke oku kukhokelela kwiindleko eziphezulu zokuvelisa i-folic acid yasekhaya, kunzima ukuphucula umxholo kunye nezinye. iingxaki.Umbhali ufunde inani elikhulu lamaxwebhu asekhaya nawangaphandle.Emva kwezilingo ezininzi kunye nezifundo, songeze i-catalyst kunye nokulawula isantya se-chlorine e-fou, sinciphisa ixesha lokuphendula kwi-1,1,3-3 ye-trichloropacetone kwiiyure ze-24, kunye ne-1,1,3-3 ye-trichloropacetone crystallization ngobunyulu obukhulu kune-99% kunye isivuno esingaphezulu kwama-45%.

II.Inxalenye yovavanyo

1. ukusabela

0 0 0 0

1. II.

　　CHACCa+Cl:—ClCH.₂CCH.₃+Cl.₂CHCCH.₃+C1CH.₂CCH.₂C1+

1. Amanyathelo ovavanyo

Kwiflask enentamo emine ene-500ml spherical condenser, isixa esithile se-acetone kunye ne-catalyst yavuselelwa kwaye yondliwa kwi-chlorine kwiqondo lokushisa lokusabela kwe-10 ~ 30 W.Qalisa ixesha, yeka ukudlula kwi-chlorine kwiiyure ezininzi emva kokuphendula, kwaye uqhubeke. ukuvuselela iyure ye-1. I-solvent ekhethekileyo efana neyona nto yongezwa kumxube obangelwayo, ixutywe ngeyure ye-1 ngelixa ipholile kwi-10 ° C crystallization, ikhupha i-1,1,3-trichloroacetone.

1. 1,1,3.Ukuzimisela okukhethiweyo kokucoceka kwe-trichloroacetone

I-Varin 3700 ye-chromatograph yegesi, i-QF ・ Ikholamu yokuzalisa e-1 kunye nesixhobo se-FID sisetyenziselwe ukukhetha ukucoceka kwenzuzo yemveliso kunye nesisombululo sekloridi.

1. Iziphumo zengxoxo
2. Impembelelo ye-catalyst kwi-chloride selectivity ibonise ukukhethwa kwe-acetone chlorination

Impembelelo enkulu, iThebhile 1 idwelisa isethi yeziphumo zovavanyo.Ukusuka kwiThebhile 1, ubuncinci bokukhethwa kwe-1,1,3-trichloroacetone yanda kakhulu (malunga ne-19.1%) ngaphandle kwe-catalyst, kwaye

　　I-compound amine catalyst yeyona nto ingcono, ukuya kuthi ga kwi-57.5%o.Iimeko zovavanyo: Innl acetone, 3nr) l chlorine,catalyst 0.6g,iqondo lobushushu 1030°C,

ixesha 18 iiyure.Ngaphakathi 12 iiyure va:3.9 Cao h;2

〜7 iiyure,vq:27 Cao h;7〜18 iiyure,VQ:3.9 ukuya h.Itheyibhile 1.Iziphumo zecatalyst ekukhetheni imveliso

1. Impembelelo yesantya sokudlula kwiklorin ekuphenduleni

Uvavanyo lwafumanisa ukuba iklorini efanayo yayinokhetho olubi lwemveliso, iphucula kakhulu ukukhethwa kwemveliso kunye nesivuno.