N,NI--bis(2-chloroethyl)carbamate i-tert-butyl ester ingasetyenziswa njenge-intermediate kwi-pharmaceutical chemistry kunye ne-organic synthesis. Kwi-organic synthesis transformations, iqela le-Boc kwisakhiwo linokususwa ngokulula ukuze kufunyanwe iqela le-carboxyl elisebenzayo.

Indlela yokwenziwa ibandakanya ukuxukuxa ngokukhawuleza ukumiswa kwe-bis-(2-chloroethyl)amine hydrochloride (5 g, 0.028 mol) kwi-dichloromethane (42 mL) nge1Isisombululo samanzi se-0% sodium hydroxide (28 mL) kubushushu bokuhlamba ngeqhwa. Isisombululo se-di-tert-butyl dicarbonate (6.1Emva koko kongezwa i-1 g, 0.028 mol) kwi-dichloromethane (28 mChemicalbook L). Emva kokuxutywa kubushushu begumbi iiyure ezili-18.5, i-dichloromethane (30 mL) yongezwa kancinci kumxube we-reaction. Emva koko la manqanaba mabini ayahlulwa. Isigaba samanzi sikhutshwa ngakumbi nge-dichloromethane (30 mL). La maleko adibeneyo e-organic ayomiswa phezu kwe-anhydrous magnesium sulfate, ahluzwe, aze axutywe ukuze kufunyanwe i-N,N-bis(2-chloroethyl)carbamate tert-butyl.